In John Chapter 15, Our Lord warns of the world's hatred. He reminds us that we will be treated by worldlings just as He was treated and that no slave is greater than his Master.
In Chapter 16:1-4, Our Lord warns of the consequences of this hatred as we approach the latter times: "All this I have told you so that you will not fall away. They will put you out of the synagogue; in fact, the time is coming when anyone who kills you will think they are offering a service to God. They will do such things because they have not known the Father or me. I have told you this, so that when their time comes you will remember that I warned you about them."
We have entered that time prophesied by Our Lord. Increasingly, people are turning away from the truth and toward doctrines of demons. And hostility toward those who faithfully preach Gospel values is intensifying. A minister is banned from preaching against homosexuality. A Catholic priest is under fire (from his own parish) for insisting that homosexuality is not genetic and for trying to preach the truth about the lifestyle. See here.
When I politely asked a group of women if they could refrain from talking loudly and laughing before the tabernacle while other Catholics tried to prepare for Holy Mass, a priest of the Worcester Diocese falsely accused me of being "angry" and stated that I would be ostracized by the parish.
God has established a hatred or an enmity. And it is destined to grow until the end of time. Saint Louis Marie Grignon de Montfort explains:
"God has established only one enmity - but it is an irreconcilable one which will last and even go on increasing to the end of time. That enmity is between Mary, his worthy Mother, and the devil, between the children and the servants of the Blessed Virgin and the children and followers of Lucifer...
The children of Belial, the slaves of Satan, the friends of the world - for they are all one and the same - have always persecuted and will persecute more than ever in the future those who belong to the Blessed Virgin, just as Cain of old persecuted his brother Abel, and Esau his brother Jacob. These are the types of the wicked and of the just. But the humble Mary will always triumph over Satan, the proud one, and so great will be her victory that she will crush his head, the very seat of his pride. She will always unmask his serpent's cunning and expose his wicked plots. She will scatter to the winds his devilish plans and to the end of time will keep her faithful servants safe from his cruel claws...Mary's power over the evil spirits will especially shine forth in the latter times, when Satan will lie in wait for her heel, that is, for her humble servants and her poor children whom she will rouse to fight against him. In the eyes of the world they will be little and poor and, like the heel, lowly in the eyes of all, down-trodden and crushed as is the heel by the other parts of the body. But in compensation for this they will be rich in God's graces, which will be abundantly bestowed on them by Mary. They will be great and exalted before God in holiness. They will be superior to all creatures by their great zeal and so strongly will they be supported by divine assistance that, in union with Mary, they will crush the head of Satan with their heel, that is, their humility, and bring victory to Jesus Christ." Taken from True Devotion to Mary.